CompletedPhase 2/3

Small Volume Simethicone Before Gastroscopy: Any Benefit?

Singapore54 participantsStarted 2015-08

Plain-language summary

A randomized controlled and endoscopist-blinded study which compares the efficacy of liquid simethicone (100mg) in 5 mls water, versus placebo ( 5mls of water), as premedication (given at least 30 minutes) before gastroscopy towards improvement of the total mucosal visibility score.

Who can participate

Age range21 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Planned for an elective diagnostic gastroscopy by the attending gastroenterologist * Age of at least 21 years old * Mentally competent and able to provide informed consent Exclusion Criteria: * Category A patients (incarcerated prisoners) * adults who are unable to give their own informed consent due to lack of mental capacity * suspected gastrointestinal bleeding * suspected impacted foreign material * suspected gastric outlet obstruction * suspected esophageal obstruction * history of dysphagia * known hypersensitivity to simethicone * previous gastrectomy

What they're measuring

Total Cumulative Mucosal Visibility Score

Timeframe: This will be calculated during the diagnostic gastroscopy, an expected duration of 10 minutes.

Trial details

NCT IDNCT02555228

SponsorChangi General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-11

Results submitted2016-02-15

View on ClinicalTrials.gov More Lesion of Stomach trials