HIPEC, Intravenous Chemotherapy and Surgery for the Treatment of Advanced GC With Peritoneal Metastasis

Inclusion Criteria: gastric cancer confirmed by endoscopic biopsy , and enhanced CT suspected to have peritoneal metastasis, including ascites, ovarian metastasis, omentum or peritoneal metastasis. * Definitely diagnosed as above stage of stomach cancer before the operation via CT or MRI, ultrasonic endoscopy and blood tumor antigen test, or through the laparoscopy if necessary * Untreated (e.g. radiotherapy, chemotherapy, target therapy and immunotherapy) * ECOG (Eastern Cooperative Oncology Group) : 0\~2 * Age: 18\~75 years old * Normal hemodynamic indices before the recruitment (including blood cell count and liver/kidney function). For example: WBC\>4.0×109/L, NEU \>1.5×109/L, PLT\>100×109/L, BIL\<1.5 times of upper limit of normal reference value, ALT and AST\<2.5 times of upper limit of normal reference value, and CRE\<1.2mg/dl * Good cardiac function before the recruitment, no seizure of myocardial infarction in past half year, and controllable hypertension and other coronary heart diseases * Not concomitant with other uncontrollable benign diseases before the recruitment (e.g. the infection in the lung, kidney and liver) * Not participating in other study projects before and during the treatment * Signed the Informed Consent Form Exclusion Criteria: * Not conforming to above inclusion criteria * Distal metastasis to lung, liver, or para aortic lymph node metastasis * Ever operation on the stomach * Operation intolerance due to other systemic basic diseases * Ever …