CompletedNot Applicable

Vitamin D Intervention in Young Adults With Severe Childhood-onset Obesity

42 participantsStarted 2012-11

Plain-language summary

Obesity is associated with lower total serum 25-hydroxycholecalciferol (S-25OHD) concentration. However, the impact of obesity on free S-25OHD is inadequately studied. A direct assay for free 25OHD was introduced recently. The aim of the study was to evaluate differences in vitamin D metabolism between young adults with severe childhood-onset obesity and normal-weight controls. Half of the obese subjects and controls will receive placebo and the other half will receive vitamin D3 50 µg daily for 12 weeks.

Who can participate

Age range15 Years – 25 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * weight-for-height ratio exceeding 60% before the age of 7 years, according to Finnish growth standards and persistence of severe obesity for at least three years in childhood * referral to the Children's Hospital, Helsinki University Hospital due to severe obesity * at the age of 7 years lived in the greater Helsinki area Exclusion Criteria: * endocrine or genetic disorders underlying obesity (e.g. Prader Willi syndrome, pseudohypoparathyroidism, hypothyroidism, hypercortisolism, diabetes

What they're measuring

change in S-25OHD

Timeframe: baseline, 6 and 12 weeks

baseline S-25OHD

Timeframe: baseline

Trial details

NCT IDNCT02549326

SponsorHelsinki University Central Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2013-05

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