Infra-slow Oscillations During Sleep (NCT02532608) | Clinical Trial Compass
CompletedNot Applicable
Infra-slow Oscillations During Sleep
Switzerland18 participantsStarted 2015-10
Plain-language summary
In this study the investigators plan to systematically characterise infra-slow EEG oscillations during sleep, explore their relationship to the microstructure of sleep, and investigate its role in the physiology and pathophysiology of sleep by co-registration of Full band EEG with polysomnography during wake and sleep in healthy subjects, after sleep deprivation, and in patients with restless legs syndrome/periodic leg movements during sleep (RLS/PLMS).
Who can participate
Age range
20 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria for all participants:
* Willingness to participate and written informed consent
* Aged 20 to 40 years at the time of screening
* Body mass index (BMI) ≤ 30
Additional inclusion criteria for subjects with RLS/PLMS:
* Either diagnosis of RLS and current IRLS score ≥ 15.
* Or frequent periodic leg movements during sleep
Exclusion criteria for all participants:
* Pregnancy or breast feeding at the time of screening
* Sleep related breathing disorders
* Current psychiatric disorders
* Current chronic treatment that may affect sleep.
* Any significant neurological disorder or other medical disease that may affect sleep.
* Any unstable medical condition.
Additional exclusion criteria for participants with RLS/PLMS:
* Current intake of dopaminergic drugs
* Current intake of other RLS relevant medication
* Intake of hypnotics
* Other significant sleep disorder except symptoms potentially related to RLS
Additional exclusion criteria for healthy participants:
* Any pharmacological treatment that may affect sleep and/or sleep related movement disorders
* Any clinically significant sleep disorders
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.