TerminatedNot Applicable

Development of Stimulator Pneumatic for Realization of Evoked Potential Allodynic/Somatosensory

Stopped: low recruitment rate

France71 participantsStarted 2011-02

Plain-language summary

The stimuli used in the evoked potentials are electrical or laser. They are started and synchronized with the collection of the EEG by signals TTL (transistor-transistor logic). Investigators propose to validate a pneumatic stimulator delivering the compressed air sync with the EEG. It has two advantages over existing stimuli: Is capable of inducing in patients an allodynic response, excessive, painful, in response to a stimulation painless rarely obtained with laser or electrical stimuli. Therefore, the pneumatic stimulation is a means to study allodynic evoked potentials unknown to date. It must be possible with a single stimulator to explore non-painful sensations and allodynic sensation , compare them with one device. The differences are the abnormal responses. This validation assumes evoked potential recording 1. somatosensory (low stimulation) then 2. allodynic (only in patients). The study therefore provides for the registration 100 potential for each of these two modalities in patients and only for the painless pneumatic modality in volunteers.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria of patients : * Major Patient * Patient affiliated or entitled to a social security scheme * Patient with neuropathic pain authenticated by the neurologist, with the presence of allodynia. * Patient has given its written consent to participate in the study Exclusion Criteria of patients : * Diseases affecting the nervous system, * Diabetes, * Patients who received chemotherapy * Pregnant woman * Nobody in emergencies * A person unable to give consent Inclusion Criteria of healthy volunteers : * Major subject * Subject affiliated or entitled to a social security scheme * Subject has given its consent to participate in the study Exclusion Criteria of healthy volunteers : * Diseases affecting the nervous system, * Diabetes, * Patients who received chemotherapy * Pregnant woman * Nobody in emergencies * A person unable to give consent

What they're measuring

composite outcomes : latencies and amplitudes of pneumatic evoked potential

Timeframe: Day 1

Trial details

NCT IDNCT02527590

SponsorCentre Hospitalier Universitaire de Saint Etienne

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2017-12