Nebulized Corticosteroid for Post Extubation Stridor in Children (NCT02523820) | Clinical Trial Compass
CompletedPhase 3
Nebulized Corticosteroid for Post Extubation Stridor in Children
Thailand144 participantsStarted 2015-01
Plain-language summary
The purpose of this study is to evaluate the efficacy and adverse effect of nebulized corticosteroid to prevent post-extubation stridor in children.
Who can participate
Age range
1 Month – 18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Children age between 1 month old - 18 year old who was intubated
Exclusion Criteria:
* Palliative care
* Anatomical abnormalities of airway; subglottic stenosis
* Neuromuscular disease with negative inspiratory force \< - 30 mmHg
* Need positive pressure after extubation
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial tested a nebulized corticosteroid specifically for post-extubation stridor in children — can you explain what post-extubation stridor is and whether it's a real risk for my child if they need to be on a breathing tube?
2Since this was a Phase 3 trial that has already been completed, have the results been published, and if so, do they suggest that nebulized corticosteroids work better, worse, or about the same as other treatments like intravenous steroids for preventing stridor after extubation?
3How does a nebulized corticosteroid differ from other ways of giving steroids, and are there specific side effects or risks from inhaling the medication that I should be aware of in a child?
4Given that this trial is completed but my child may be facing extubation soon, would the findings from this study change how your team currently manages post-extubation stridor, or is there a different standard-of-care approach you would recommend instead?
5If my child does develop stridor after being taken off the breathing tube, what is the treatment plan, and is a nebulized corticosteroid something your team would consider using based on what this trial found?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.