Lower Fluorescein Sodium Dose on Confocal Laser Endoscopy Image Quality and Yellow Discoloration of the Skin

Inclusion Criteria: * Only those with normal mucosa and minor gastritis from 18 were included. * patients with aged 18 years to 80 years * patients with normal mucosa and minor gastritis * willing to provide informed consent Exclusion Criteria: * serious coagulopathy dysfunction, severe cardiopulmonary disease, bronchial asthma, liver and kidney dysfunction, allergy to fluorescein, pregnancy women or breast feeding. * patients with peptic ulcer, gastric cancer, remnant stomach, acute serious gastritis were also excluded. * unwilling to provide informed consent