WithdrawnPhase 3

Comparison of Progel Sealant to Standard of Care (SOC) for Patients Undergoing Decortication

0Started 2015-12

Plain-language summary

The goal of this clinical research study is to compare Progel® (a type of surgical sealant that is made from human blood products) to the standard of care (talcum powder) to learn if one method is better than the other for preventing air leaks in patients having a pleurectomy decortication.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. All patients with mesothelioma or other pathologies undergoing a pleurectomy decortication at MD Anderson Cancer Center
✓. Adequate preoperative renal function documented by serum creatinine of \< 1.5 mg/dl or calculated creatinine clearance \> 50 ml/min

Exclusion criteria

✕. Patients unable to consent for the procedure
✕. Patients with a history of allergy to human proteins
✕. Patients who may have insufficient renal capacity for clearance of Progel® polyethylene glycol load

What they're measuring

Time to Resolve Air Lung Leak After Pleurectomy Decortication

Timeframe: Participants followed for the duration of hospital stay, at least 5 days.

Trial details

NCT IDNCT02511600

SponsorM.D. Anderson Cancer Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-12

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