Human Plasma Fatty Acid Oscillations

Inclusion Criteria: * Volunteers must be in good health as based on medical history, physical examination, vital signs, and laboratory tests as deemed by PI, BMI of 27-32; * Volunteers are capable of giving informed consent; * 18-65 years of age; * Non-smoking; and * Non-pregnant, female subjects must consent to a urine pregnancy test. * Control subjects eat less than 25% of their caloric intake after dinner without nocturnal ingestions; * NES patients have to meet both of the criteria for nocturnal ingestions and evening hyperphagia; eat 30% of their caloric intake after dinner with nocturnal wake ups to eat at a frequency of ≥ 5 times per week Exclusion Criteria: * Recent travel across time zones (within the past month); * Planned travel across time zones during the planned study activities; * Volunteers with irregular work hours, e.g. night shifts or swing shift schedule; * Subjects, who have received an experimental drug, used an experimental medical device within 30 days prior to screening, or who gave a blood donation of ≥ one pint within 8 weeks prior to screening; * Subjects with any abnormal laboratory value or physical finding that according to the investigator may interfere with interpretation of the study results, be indicative of an underlying disease state, or compromise the safety of a potential subject; * Diagnosis of severe depression, lifetime diagnosis of bipolar disorder or any psychotic disorder; * Prescription and non-prescription (OTC) medication; me…