CompletedPhase 4

Locally Delivered Doxycycline Adjunct to Nonsurgical Periodontal Therapy.

Brazil30 participantsStarted 2010-03

Plain-language summary

The aim of this clinical study is to asses the effect of ultrasonic periodontal debridement associated to locally delivered doxycycline (20%) by PLGA microspheres on chronic generalized periodontitis treatment.

Who can participate

Age range35 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Chronic generalized periodontitis (AAP,1999); * At least 7 sites with probing depths \>5mm, and 2 sites with probing depth \>7mm; * At least 20 teeth present; * Systemically healthy. Exclusion Criteria: * Had received periodontal care 6 months prior to the study; * Had taken medications known to interfere with periodontal health and healing 6 months prior to the study; * Pregnants or lactants; * Smokers; * Sensitive to doxycycline.

What they're measuring

Probing depht (PD)

Timeframe: 6 months

Trial details

NCT IDNCT02487186

SponsorUniversity of Campinas, Brazil

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-12

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