CompletedPhase 2/3

Vaginal Estradiol Pretreatment in Labour Induction With Misoprostol

Egypt200 participantsStarted 2015-06

Plain-language summary

To assess the effect of vaginal estradiol pretreatment before vaginal misoprostol on labor induction.

Who can participate

Age range18 Years – 35 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria: * Maternal age ≥ 18 years old. * Gestational age ≥ 37 wks to 41 wks. * BMI between 20 kg/m2 and 35kg/m2. * Vertex presentation. * Singleton pregnancy. Exclusion criteria: * Multiple pregnancy. * Non vertex presentation. * Absolute or relative contraindication to vaginal delivery e.g. (Placenta previa, fibroid uterus, uterine anomalies, previous uterine surgery). * PROM. * IUFD. * Fetal distress.

What they're measuring

Time to cervical ripening.

Timeframe: 24 hours

Trial details

NCT IDNCT02485821

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-02

View on ClinicalTrials.gov More Failed Induction of Labor trials