Electroacupuncture for Tapering Off Long-term Benzodiazepine Use (NCT02475538) | Clinical Trial Compass
UnknownNot Applicable
Electroacupuncture for Tapering Off Long-term Benzodiazepine Use
China144 participantsStarted 2015-07
Plain-language summary
This study aims to examine the efficacy of electroacupuncture for tapering benzodiazepines in long-term users. All eligible subjects will be randomized in a ratio of 1:1 to (1) Electroacupuncture combined with gradual tapering; and (2) Placebo acupuncture combined with gradual tapering.
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* aged ≥ 18 years
* taking benzodiazepines (World Health Organization Anatomical, Therapeutic and Chemical classification system codes N05BA, N05CD, N05CF, and M03BX07)) on more than 50% of days for at least 3 months and during their prospective 2-week record prior to baseline
* willing to withdraw their benzodiazepine use during the study,
Exclusion Criteria:
* any relapse of psychiatric disorder in the past year that required intervention,
* Hospital Anxiety and Depression Scale depression or anxiety as a tool (subscore ≥ 8) which indicates subjects with possible depression or anxiety
* have any unstable psychiatric conditions or serious physical illnesses which are judged by the investigator to render unsuitable or unsafe;
* have valvular heart defects or bleeding disorders, taking anticoagulant drugs, or are fitted with any implanted electrical device such as pacemaker, defibrillator, or brain stimulation,
* have received any acupuncture during the previous 6 months prior to baseline,
* are pregnant, breast-feeding or of childbearing potential but not using adequate contraception,
* have infection or abscess close to the site of selected acupoints and in the investigator's opinion inclusion is unsafe and
* significant suicidal risk as rated by the Hamilton Depression Rating Scale item on suicide (a score ≥ 3)
What they're measuring
1
The proportion of participants who successfully discontinued benzodiazepines