CompletedPhase 4

Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients

42 participantsStarted 2012-12

Plain-language summary

The purpose of this study is to determine whether full-mouth disinfection is effective in the initial periodontal treatment of generalized aggressive periodontitis on clinical parameters, gingival crevicular fluid interleukin-1β (IL-1β) and interleukin-17 (IL-17) and periodontal pathogen levels compared with conventional initial periodontal treatment and full-mouth initial periodontal treatment. The investigators' hypothesis is to test whether full-mouth disinfection in the initial periodontal treatment of generalized aggressive periodontitis enhance the clinical, biochemical and microbiological parameters in comparison to conventional initial periodontal treatment and full-mouth initial periodontal treatment.

Who can participate

Age range18 Years – 35 Years

SexALL

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Inclusion Criteria: * No systemic diseases that could influence the outcome of the therapy * No smoking * No medications affecting periodontal tissues * No pregnancy or lactation * Presence of at least 15 teeth Exclusion Criteria: * Received antibiotic treatment in the previous 3 months * Smokers * Pregnancy and lactation * Received periodontal treatment in the previous 6 months * Presence of less than 15 teeth * Presence of systemic diseases

What they're measuring

Probing Depth

Timeframe: 6 months after initial periodontal treatment

Trial details

NCT IDNCT02466646

SponsorMarmara University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2014-09

Results submitted2020-04-13

View on ClinicalTrials.gov More Aggressive Periodontitis trials