TerminatedNot Applicable

The Use of Point-of-Care Ultrasound in the Diagnosis of Acute Infectious Mononucleosis in the Emergency Department

Stopped: COVID pandemic

Canada200 participantsStarted 2016-04

Plain-language summary

The purpose of this study is to determine if splenomegaly on point-of-care ultrasound (POCUS) is an accurate and user-friendly surrogate to the heterophile antibody test and Epstein-Barr Virus (EBV) serologies to diagnose acute mononucleosis infection in patients presenting with sore throat to the Emergency Department (ED).

Who can participate

Age range10 Years – 35 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged between 10 and 35 year-old presenting to the ED with suspected acute infectious mononucleosis Exclusion Criteria: * Chronic infectious disorders (eg. tuberculosis, malaria, HIV, syphilis) * Inflammatory disorders (eg. sarcoidosis, amyloidosis, systemic lupus erythematosus, Felty syndrome) * Proliferative disorders (eg. lymphoma, leukemia, essential thrombocytopenia, polycythemia vera) * Congestive disorders (eg: cirrhosis, portal hypertension, right heart failure, congenital heart disease) * Chronic haemolytic anemia (eg. sickle cell, thalassemia, hereditary spherocytosis) * Storage diseases (eg. Gaucher, Niemann-Pick) * Splenectomy * Inability to give informed consent

What they're measuring

Presence of splenomegaly (maximal splenic cranio-caudal length) on point-of-care ultrasound

Timeframe: 12 months

Trial details

NCT IDNCT02463669

SponsorJewish General Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-10-04

View on ClinicalTrials.gov More Infectious Mononucleosis trials