Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)

Inclusion Criteria: * Meets genetic or clinical diagnostic criteria for TSC (Tuberous Sclerosis), the latter based on current recommendations for diagnostic evaluation, such as physical exam, neuroimaging, and echocardiogram. * Age criteria: over 18 months of age at time of enrollment. * Is diagnosed or suspected to have ASD and/or ID. * Primary communicative language is English Exclusion Criteria: * Has taken an investigational drug as part of another research study, within 30 days prior to study enrollment. * For subjects involved in imaging biomarker assessment: contraindications to 3T MRI scanning, such as metal implants/non-compatible medical devices or medical conditions, including vagus nerve stimulator. * For subjects involved in EEG/ERP biomarker assessment: contraindications to EEG/ERP, such as uncooperative or destructive behaviors preventing lead placement or capture by ERP/VEP equipment. Under age 2 or above age 11 at the time of enrollment. * Unwilling or unable to comply with study procedures and assessments.