Basic treatment of type 2 diabetes should focus on diet, physical activity and lifestyle. Nevertheless, in early and late stage of T2DM, lifestyle intervention is mostly substituted by pharmacological intervention, although lifestyle modification and dietary treatment would be favourable. The researchers therefore investigate dietary strategies such as low-carb and very-low calory diets regarding their potential to improve metabolism and body weight in (mostly) long-term T2DM patients.
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change in insulin secretion (glucagon stimulation test)
Timeframe: 3 weeks, 1 year
change in hepatic fat content (MR-S)
Timeframe: 3 weeks, 1 year
change in insulin secretion in the mixed-meal tolerance test (MMTT) - combined parameter
Timeframe: 3 weeks, 1 year
change in insulin sensitivity in the mixed-meal tolerance test (MMTT) - combined parameter
Timeframe: 3 weeks, 1 year
change in blood glucose profile in the mixed-meal tolerance test (MMTT) - combined parameter
Timeframe: 3 weeks, 1 year