Diagnostic of Puumala Virus Infection in France

Inclusion Criteria: Hospitalized patients, male or female, more than 18 years old and less than 76 years old1: * having at admission or within 8 days preceding admission a pain , a documented febrile syndrome (body temperature ≥ 38°C) and a platelet count \< 150 G/L, * exposed to PUUV infection (for the last 6 weeks) or living in a French municipality where Hantavirus infection cases have been recorded during the 2003-2013 period or in a municipality bordering one of them , * giving their written consent after being informed of the research and the collection of data, and blood \& urine samples. NB: persons in emergency situation will be proposed to participate because their situation may affect the performances of laboratory diagnostics. Exclusion Criteria: Hospitalized patients: * who are known to have been previously diagnosed infected by an hantavirus (medical records and/or laboratory results), * who are known to present stable thrombocytopenia, * who, according to the medical staff, would not adhere to the protocol, * for whom the health status, according to the medical staff, may interfere with the study or is not compatible with the sampling planned in the study. NB: Pregnant, parturient or breast-feeding women as well as patients under psychiatric care or patients subject to a legal protection order will be not proposed to participate.