CompletedPhase 1/2

Treatment of Refractory Auditory Verbal Hallucinations With tDCS in Schizophrenia

South Korea10 participantsStarted 2016-08

Plain-language summary

The purpose of this study is to exploratively evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in patients with schizophrenia who experience persistent auditory verbal hallucinations after adequate antipsychotics therapy for over three months.

Who can participate

Age range19 Years – 50 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with schizophrenia by the Diagnostic and Statistical Manual of Mental Disorders, Fourth edition, Text Revision (DSM-IV-TR) * Presence of auditory hallucination after three months' trial of antipsychotics of adequate dose * The Hamilton Program for Schizophrenia Voices Questionnaire (HPSVQ) score is at least 8 Exclusion Criteria: * Significant brain pathology including head trauma, seizure, meningitis * Intellectual disability (IQ \< 70) * Severe personality disorder * Substance use disorder (except nicotine) * Severe medical illness * Disability in the sensory organs * Pregnancy

What they're measuring

Auditory hallucination change by changes in The Psychotic Symptom Rating Scales (PSYRATs) Auditory hallucinations subscale score

Timeframe: approximately 2 weeks

Trial details

NCT IDNCT02451371

SponsorSeoul National University Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-12

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