The purpose of this study is to determine whether giving extra arginine to patients with sickle cell disease seeking treatment for vaso-occlusive painful events (VOE) will decrease pain scores, decrease need for pain medications or decrease length of hospital stay or emergency department visit.
Age range
7 Years – 21 Years
Sex
ALL
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The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Pharmacokinetics of IV arginine, measured by plasma arginine concentration over time
Timeframe: Day 1 through study completion, an average of up to 7 days
Change in nitric oxide metabolites
Timeframe: Baseline, day 1 through study completion, an average of up to 7 days