CompletedPhase 4

Efficacy and Safety of Prophylactic Use of an Antibiotic for Medical Thoracoscopy

India100 participantsStarted 2015-01

Plain-language summary

This is a prospective study to assess the efficacy and safety of a single dose of cefazolin 2g IV for the prophylaxis of surgical site and pleural space infections in patients undergoing medical thoracoscopy.

Who can participate

Age range12 Years – 80 Years

SexALL

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Inclusion criteria

✓. Age ≥12 years
✓. Medical thoracoscopy being performed for a pleural effusion for any of the three indications: diagnosis, pleurodesis, or adhesiolysis

Exclusion criteria

✕. Age ≥80 years
✕. Pao2/FIO2\< 300;
✕. Hemodynamic instability
✕. Myocardial infarction or unstable angina in the last 6 wk
✕. Lack of pleural space due to adhesions
✕. Uncorrected coagulopathy
✕. Failure to provide informed consent
✕. Patients already taking any antibiotic due to any reason

What they're measuring

Efficacy as assessed by occurrence of wound infection or pleural space infection

Timeframe: 2 months

Trial details

NCT IDNCT02446782

SponsorPost Graduate Institute of Medical Education and Research, Chandigarh

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-04

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