CompletedNot Applicable

Trial of Negative-pressure Wound Therapy Use in Conflict-related Extremity Wounds

Iraq, Jordan116 participantsStarted 2015-06

Plain-language summary

There is a treatment method called negative-pressure wound therapy (NPWT) that is well established and used for the treatment of wounds. The method involves the application of a wound dressing through which a negative pressure is applied. Due to a plastic film overlaying the wound the risk of wound contamination is reduced. NPWT is considered to promote wound healing and prevent infection and has previously been used in the treatment of acute war associated wounds with satisfactory results. The aim of this study is to compare NPWT with conventional wound dressings in the treatment of war-associated extremity wounds and evaluate which method is more effective.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients ≥ 18 years of age with extremity blast- or gunshot-wound(s). In case of multiple wounds the extremity wound with the estimated largest area is selected. Exclusion Criteria: * Wounds presenting \>72 hours following initial trauma. * Wounds that are considered ready for primary closure by suture or split-thickness skin graft.

What they're measuring

Early wound closure

Timeframe: Day five +-1

Cost-effectiveness comparing outcomes from NPWT and standard treatment

Timeframe: Days (between 1 and 50)

Trial details

NCT IDNCT02444598

SponsorKarolinska Institutet

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-10

View on ClinicalTrials.gov More Wounds, Gunshot trials