Performance of FISH for the Diagnosis of Malignant Biliary Strictures in Thai Patients (NCT02442167) | Clinical Trial Compass
CompletedNot Applicable
Performance of FISH for the Diagnosis of Malignant Biliary Strictures in Thai Patients
101 participantsStarted 2010-03
Plain-language summary
Fluorescence in situ hybridization (FISH) has improved the diagnostic performance of cytology for evaluation of malignant biliary strictures in the US and Europe. The utility of FISH for diagnosis of biliary strictures in Asia is currently unknown. The investigators conducted a prospective study in 2 university hospitals to determine diagnostic performance of FISH for the diagnosis of malignant biliary strictures in Thai patients.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age \> 18 years
* Clinical suspicion of malignant biliary tract strictures
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial tested a technique called FISH to diagnose whether a bile duct stricture is cancerous — how does FISH compare to the standard tests my doctor is already using to evaluate my stricture?
2Since this study was done specifically in Thai patients, is there any reason to think the FISH test's accuracy might be different for someone with my background or in my current medical setting?
3The trial was measuring how sensitive FISH is at detecting malignancy — does that mean there's still a meaningful chance it could miss a cancer, and how would my doctor handle a negative result if suspicion remains high?
4Now that this trial is completed, are its findings already being used in clinical practice, or is FISH still considered experimental when it comes to diagnosing biliary strictures like mine?
5Given that this was a diagnostic study rather than a treatment trial, how would confirming or ruling out malignancy with FISH actually change the treatment options my doctor would recommend for me?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Sensitivities with 95% confidence intervals of FISH