CompletedNot Applicable

Delayed Embryo Transfer in Poor Responders

Egypt400 participantsStarted 2015-04

Plain-language summary

Poor ovarian response indicates inadequate ovarian response to ovarian stimulation. In the current study the investigators will attempt to compare antagonist and short protocols regarding oocyte as well as embryo quantity and quality. Frozen embryo transfer will be performed in order to abolish iatrogenic effect of stimulation drugs on implantation. Still implantation and pregnancy rates are considered secondary outcomes.

Who can participate

Age range25 Years – 45 Years

SexFEMALE

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Inclusion criteria

✓. Advanced maternal age (≥40 years) or any other risk factor for POR;
✓. A previous POR (≤3 oocytes with a conventional stimulation protocol);
✓. An abnormal ovarian reserve test (i.e. Antral follicle count (AFC) \<5-7 follicles or Antimullerian hormone (AMH) \<0.5-1.1 ng/ml).

What they're measuring

Number of Metaphase II (MII) oocytes

Timeframe: 9-14 days from stimulation

Number of good embryos

Timeframe: 3-5 days after ovum pickup

Trial details

NCT IDNCT02431689

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-05

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