Arterial Calcification in the Diabetes (NCT02431234) | Clinical Trial Compass
UnknownNot Applicable
Arterial Calcification in the Diabetes
France169 participantsStarted 2014-02
Plain-language summary
The blood concentration of the protein RANKL could be predictive of the calcification of the leg arteries, which is a major complication occurring during diabetes. The objective of the DIACART study is to show that blood RANKL concentration predict the progression of calcification of the leg arteries in diabetic patients, independently of other cardiovascular risk factors.
Who can participate
Age range
50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
* type 2 diabetes
* women over 60
* men over 50 years
* men and women with known coronary artery disease
Non-Exclusion criteria:
* severe renal failure
* immunodeficiency
* acute infectious or inflammatory disease
* history of bypass surgery or sub-popliteal angioplasty
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is studying RANKL levels in the blood as a way to understand arterial calcification in diabetes — can you explain what RANKL is and why its measurement might be relevant to my vascular health?
2The study involves conditions like Monckeberg medial calcific sclerosis and arteriosclerosis obliterans, which I hadn't heard of before — do I have either of these types of arterial calcification, and is that something we should be monitoring more closely?
3Since this trial is listed as 'Phase NA' and appears to be an observational or measurement study rather than a treatment trial, does participating mean I'd receive any intervention, or would I just be providing blood samples and data?
4The recruitment status for this trial is listed as unknown, so is it even currently enrolling patients, and if not, are there similar studies or registries you'd recommend I look into?
5Given that this trial focuses on understanding the biology of vascular calcification in diabetes rather than testing a new treatment, would you say my current diabetes management plan is already addressing the underlying risks this study is investigating?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.