Effect of Transjugular Intrahepatic Portosystemic Shunt on Gut Microbiota in Cirrhotic Patients

Inclusion Criteria: * Cirrhotic patients who received TIPS; * Treatment-naive to TIPS and major operation involving liver such as surgical shunt, hepatic resection and liver transplantation) Exclusion Criteria: * Uncontrolled infection or sepsis; * Hepatobiliary or pancreatic malignancy or biliary obstruction; * Vital organ dysfunction; * Administration of antibiotics (after TIPS and 2 weeks before TIPS); * Cachexia; * Pregnant or breeding women