CompletedPhase 4

Role of Acetazolamide and Hydrochlorothiazide Followed by Furosemide in Treating Nephrotic Edema

20 participantsStarted 2015-04

Plain-language summary

The purpose of this study is to determine whether using furosemide following acetazolamide is effective in treating refractory edema associated with nephrotic syndrome.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Having refractory edema due to nephrotic syndrome
✓. Having GFR\>60 ml/min/1.73m2
✓. Being able to come for weekly visit
✓. Having the minimum age of 18 years
✓. Signing the informed consent form

Exclusion criteria

✕. Hypokalemia
✕. Pregnancy
✕. Renal transplant
✕. active malignancy or infection
✕. acidosis
✕. Using NSAIDs
✕. Having another causes of edema including liver cirrhosis, heart failure
✕. Neurologic or psychiatric problem hindering adherence to the study protocol

What they're measuring

Change from baseline in weight at the end of third week

Timeframe: Baseline and at the end of the third week

Trial details

NCT IDNCT02427880

SponsorShiraz University of Medical Sciences

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-06

View on ClinicalTrials.gov More Nephrotic Syndrome trials