Active — Not RecruitingEarly Phase 1

The Effect of Topical Anesthetics on Patients' Pain and Operative Experience During Treatment With QSwitched Laser

United States48 participantsStarted 2015-04

Plain-language summary

This study will conduct a split-face and -body randomized control trial to compare lidocaine 2.5%/prilocaine 2.5% topical anesthetic (LPTA), lidocaine 7%/tetracaine 7% topical anesthetic (LTTA), and placebo vechicle (PV) on patients' pain perceptions with Q-switched 532nm laser for the treatment of lentigines and/or photorejuvenation.Subjects will fill out a pain score on a visual analog scale (VAS) with 0 being no pain and 10 being most pain after each treatment area is completed.

Who can participate

Age range25 Years – 65 Years

SexFEMALE

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Inclusion criteria

✓. Patients who have moderate lentigines and/or photodamage and desire laser toning.
✓. Females 25-65 years of age.
✓. In good health.
✓. Have Fitzpatrick phototype I-III.
✓. Willingness and the ability to understand and provide informed consent and communicate with the investigator/study staff.

Exclusion criteria

✕. Younger than 25 or older than 65 years of age.
✕. Pregnant or lactating.
✕. Is a male.
✕. Has received the following treatments on the face:
✕. Has an active infection on the face or upper inner arms (excluding mild acne).
✕. Is allergic to lidocaine, tetracaine, or prilocaine.
✕. Has kidney disease and/or liver disease.
✕. Has G-6-PD and/or pseudocholinesterase deficiency.

What they're measuring

visual analog score (VAS) pain rating

Timeframe: Day of treatment

Trial details

NCT IDNCT02427724

SponsorNorthwestern University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12

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