FLuorescence Identification of Melanoma by a Multicenter Based Algorithm (FLIMMA)

Inclusion Criteria: * Patients ≥ 18 years of age * Male or female * Patients having pigmented lesions with suspicion of dysplastic nevus or melanoma, in whom an excision is performed in order to exclude or diagnose malignant melanoma * Patients who gave their written informed consent. Exclusion Criteria: * Patients with skin type V and VI according to Fitzpatrick's scale; * Where there is a risk that the scanning head is torn off be-cause the patient cannot be placed at rest (e.g. due to motoric disorders like tremor, convulsions, tics, compulsive acts * Patients who cannot understand the patient information and provide informed consent * Deep dermal lesions ≥ 5 mm beneath the stratum corneum * Clinically or reflected-light microscopically obviously non-melanocytic lesions * Peri- and subungual lesions * Mucosal lesions * Lesions with trauma, erosion (superficial defect), excoriation (defect down to the basement membrane) or ulceration (deep substantial defect) on more than 50 % of the lesion area (measurements must in any case not be carried out directly on the trauma, erosion, excoriation or ulceration) * Tattooed lesions * Pregnant or breast feeding women * Patients suffering from albinism * Lesions with dominant (\>50%) regression * Lesions which are not suitable to fix the scanning cap