Comparative Study on the Effects of Sublingual Misoprostol in Addition to Standard AMTSL in Low R… (NCT02424201) | Clinical Trial Compass
UnknownEarly Phase 1
Comparative Study on the Effects of Sublingual Misoprostol in Addition to Standard AMTSL in Low Risk Parturients in LASUTH, Ikeja.
660 participantsStarted 2015-06
Plain-language summary
Postpartum haemorrhage is the leading cause of maternal haemorrhage globally. With active management of labour 3 to 16.5% of parturients still experience postpartum haemorrhage. Hence the need for an effective oxytocic in third stage of labour.
Who can participate
Age range
15 Years – 45 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* singleton in longitudinal lie and cephalic presentation
Exclusion Criteria:
* refusal of consents, multiple gestation
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is listed as Early Phase 1 and its recruitment status is unknown — does that mean it's still actively enrolling, or has it been completed or stopped, and would it even be an option for me?
2The study is adding sublingual misoprostol on top of the standard active management of the third stage of labour (AMTSL) — can you explain what that combination means in practice for me during and right after delivery, and are there any known side effects from taking both at once?
3Since this is an Early Phase 1 study focused on measuring mean blood loss, what does that phase tell us about how much safety and effectiveness data already exists for this specific combination, and how does that compare to just receiving the standard AMTSL that hospitals already use?
4The trial is being conducted at LASUTH in Ikeja — if I'm not delivering at that hospital, would participating even be logistically possible, and would transferring my care there be worth considering?
5If I'm considered low risk for postpartum haemorrhage, is there a reason to consider joining a study like this rather than simply receiving the standard treatment my care team already offers?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.