CompletedNot Applicable

A Provocation Study Using Biogenic Amines to Show the Efficacy of Oral Diamine Oxidase Supplementation

Austria72 participantsStarted 2014-02

Plain-language summary

This study aims to define a provocation test for histamine intolerance (aka. biogenic amine intolerance syndrome) and test the capability of an oral enzyme supplementation to ameliorate this condition.

Who can participate

Age range19 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Persons suspected of suffering from BAIS (BAIS Score ≥ 50) according the the questionaire used for histamine intolerance so far Exclusion Criteria: * pregnancy * coronary heart disease * labile hypertension * bronchial asthma * periodical therapy using H1-blockers * chirurgical intervention with the GI tract within the previous 3 months * participation in a clinical trial within the previous 4 weeks

What they're measuring

Reduction of biogenic amine symptoms (determined via symptom score)

Timeframe: 24 hrs after start of provocation

Trial details

NCT IDNCT02418221

SponsorIPSC AG

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2014-11

View on ClinicalTrials.gov More Histamine Intolerance trials