CompletedNot Applicable

Postoperative Respiratory Monitoring After Neuraxial Opioid Administration for Cesarean Delivery

United States80 participantsStarted 2015-04

Plain-language summary

Respiratory depression occurs in labor and delivery; noticeably when neuraxial opioids are given.Pathophysiological respiratory depression -failure to respond to hypercapnia or hypoxia - is challenging to measure clinically.American Society of Anesthesiologist guidelines recommend suitable respiratory monitoring for 24 hours post cesarean delivery (CD). Use of capnograph will enable us to assess breath-by-breathe respiration in a population receiving neuraxial opioids - potentially at risk for respiratory depression. Our aim is to assess our ability to capture maternal postpartum respiratory parameters in a cohort following opioid neuraxial administration for CD.

Who can participate

Age range18 Years – 45 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * American Society of Anesthesiologists physical status class I or II * Age between 18 and 45 * Gestational age greater than 37 completed weeks * Singleton pregnancy. Exclusion Criteria: * Contraindication for neuraxial analgesia (bleeding diathesis, neuropathy, severe scoliosis, previous spine surgery, local anesthetic allergy) * Allergies to postoperative medication (opioids, NSAIDs, acetaminophen) * Chronic opioid use * Opioid administration in the previous 12 hours * Inability to adequately understand the consent form * Blocked nose or nasal deformity.

What they're measuring

CO2 monitoring

Timeframe: 24 hrs

Trial details

NCT IDNCT02417038

SponsorStanford University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2016-04-15

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