CompletedNot Applicable

Lyme Borreliosis and Early Cutaneous Diagnostic

France84 participantsStarted 2015-08-06

Plain-language summary

Test and evaluate a new diagnostic method (SRM-MS/MS: Selected Reaction Monitoring- Mass spectrometry) for Lyme Borreliosis on human skin biopsies. Patients included are those with the early skin manifestation (erythema migrans). This new proteomic method will be compared to the two existing method: culture of Borrelia and PCR detection of Borrelia (DNA detection of the bacteria).

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * Erythema migrant as criteria EUCALB or atypical form associated to tick's sting * Patient having signed a consent * Patient affiliated to a social security scheme Exclusion Criteria: * Prior treatment with antibiotics * Erythema migrans on the face * Bleeding disorders * Anticoagulant treatment * Inability to give clear information (subject in an emergency situation, understanding of the topic difficulty, ...)

What they're measuring

Compare the sensitivity (percentage of positive tests) of the SRM / MS-MS to techniques of PCR and culture Borrelia

Timeframe: One year study

Trial details

NCT IDNCT02414789

SponsorUniversity Hospital, Strasbourg, France

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-02-01

View on ClinicalTrials.gov More Erythema Migrans trials