UnknownNot Applicable

Observational Retrospective Study on Treatment and Outcomes in Patients With Low-grade Serous Ovarian Cancer

Italy150 participantsStarted 2014-10

Plain-language summary

The purpose of this study is to retrospectively evaluate treatments and outcomes of patients with low grade serous ovarian carcinomas in Italy.

Who can participate

Age range18 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosis low-grade serous ovarian carcinoma * OR invasive recurrence after surgical resection of borderline serous ovarian carcinoma * Availability of archival tumor specimen (paraffin embedded block) for central analysis and evaluation for mutations * Age \> 18 years * Signed informed consent Exclusion Criteria: * High-grade serous, mucinous, endometrioid, or any other non-low-grade serous ovarian carcinoma * Unavailability of archival tumor specimen

What they're measuring

risk of recurrence in patients with low-grade serous ovarian carcinoma

Timeframe: two years

number of patients with objective tumor response after receiving chemotherapy

Timeframe: 6 months

number of patients with objective tumor response after receiving hormone therapy

Timeframe: 6 months

number of patients with objective tumor response after receiving combination hormonal and chemotherapy

Timeframe: 6 months

progression free survival

Timeframe: 2 years

overall survival

Timeframe: 5 years

Trial details

NCT IDNCT02408536

SponsorNational Cancer Institute, Naples

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-12

Contact for this trial

Francesco Perrone, MD PhD

+39 081 5903571 datamanager@usc-intnapoli.net

View on ClinicalTrials.gov More Low-grade Serous Ovarian Carcinoma trials