Investigating Meningococcal Vaccines in Adults

Inclusion Criteria: * Participant is willing and able to give informed consent for participation in the study. * Male or Female, aged 18 years to 60 years inclusive on the day of first vaccination. * To be in good health as determined by medical history, physical examination and clinical judgment of the investigators. * Agree (in the Investigator's opinion) to comply with all study requirements * Agree to allow his or her General Practitioner (and/or Consultant if appropriate), to be notified of participation in the study * Agree to provide their National Insurance/Passport number for the purposes of TOPS registration and bank account information for the purpose of reimbursement for the duration of their participation. Exclusion Criteria: * Have any known or suspected impairment or alteration of immune function, resulting from, for example: * Congenital or acquired immunodeficiency (including IgA deficiency) * Human Immunodeficiency Virus (HIV) infection or symptoms/signs suggestive of an HIV-associated condition * Autoimmune disease * Receipt of immunosuppressive therapy such as anti-cancer chemotherapy or radiation therapy within the preceding 12 months or long-term systemic corticosteroid therapy. * Chronic illness that could interfere with immunological function or donation of the required volumes of blood (e.g. cardiac or renal disease, diabetes, or auto-immune disorders). * Receipt of a live vaccine within 4 weeks prior to vaccination or a killed vaccine w…