CompletedNot Applicable

Left Atrial Volume Index in Asymptomatic Aortic Stenosis

Denmark100 participantsStarted 2014-01

Plain-language summary

Aortic stenosis results in increased filling pressures of the heart. Size and function of the left atrium may be a marker for more advanced heart disease (heart failure) in patients with severe aortic stenosis, not presenting any apparent symptoms. The goal of this study is to establish the importance and possible implications of left atrial dilation in asymptomatic patients with aortic valve stenosis.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Asymptomatic severe aortic stenosis (Vmax \> 3.5 m/sec and aortic valve area \< 1 cm2). Exclusion Criteria: * Moderate LV systolic dysfunction (LVEF \< 50%) * Concomitant moderate-severe aortic valve regurgitation * Concomitant moderate-severe mitral valve regurgitation * Moderate to severe nephropathy * Chronic or persistent atrial fibrillation * Implanted pacemaker or cardio defibrillator * Disability to exercise testing.

What they're measuring

Functional Capacity

Timeframe: 2 years

Trial details

NCT IDNCT02395107

SponsorOdense University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2016-06

View on ClinicalTrials.gov More Aortic Valve Stenosis trials