CompletedNot Applicable

Intraoperative Lung-Protective Ventilation in Neurosurgery

China360 participantsStarted 2015-10

Plain-language summary

The purpose of this study is to explore the effectiveness of lung-protective ventilation during general anesthesia for neurosurgical procedures on postoperative pulmonary outcome, compared with traditional ventilation.

Who can participate

Age range40 Years – 80 Years

SexALL

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Inclusion criteria

✓. \> 40 years ,and \< 80 years
✓. Scheduled for neurosurgery
✓. After informed consent has been obtained
✓. With an expected duration of ≥ 4 hours
✓. preoperative risk index for pulmonary complications≥ 2
✓. Glasgow Coma Scale \>8

Exclusion criteria

✕. Mechanical ventilation of \> 1 hour within the last 2 weeks before surgery
✕. Body mass index ≥ 35 kg/m2
✕. Acute respiratory failure (pneumonia, acute lung injury or acute respiratory distress syndrome)
✕. Emergency surgery
✕. Severe cardiac disease
✕. Progressive neuromuscular illness
✕. Pregnancy
✕. Refusal to participate

What they're measuring

Postoperative pulmonary complications

Timeframe: 7 days after surgery

Trial details

NCT IDNCT02386683

SponsorCapital Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-03

View on ClinicalTrials.gov More Ventilator-induced Lung Injury trials