A Study to Evaluate the Efficacy of an Acellular Dermal Template for the Treatment of Full Thickness Skin Defects

Inclusion Criteria: * Age ≥18 years (for Zurich: ≤ 18 years) * Full thickness skin defects configured in such a way that two comparable and measurable areas can be grafted, both of minimally 3x3 cm * ≤ 50% TBSA full thickness skin defects at time of intervention * Informed consent by the patient and/or legal representatives. Exclusion Criteria: * Patients with infected wounds * Full thickness skin wounds located in face and/or genitals will not be included * Pregnant or breast feeding females * Patients with known concomitant medical conditions that may interfere with normal wound healing (e.g. immune deficiency, HIV, uncontrolled diabetes, treatment with corticoid therapy, collagenoses, cancer) * Known allergy against porcine collagen or elastin * Patients that are expected (according to the responsible medical doctor) to be non-compliant to the study protocol. (This includes patients with severe cognitive dysfunction/impairment and severe psychiatric disorders) * Previous enrolment of the patient into the current study