Early ART Initiation Among HIV-positive Pregnant Women in Central Mozambique (NCT02371265) | Clinical Trial Compass
CompletedNot Applicable
Early ART Initiation Among HIV-positive Pregnant Women in Central Mozambique
Mozambique761 participantsStarted 2012-04
Plain-language summary
The overall objective of the study is to develop and test a pilot intervention in central Mozambique to implement the new WHO "Option B+" guidelines that seek to increase the proportion of HIV-positive pregnant women in six antenatal care clinics who start antiretroviral therapy (ART) prior to delivery, and are retained in care after 90- days.
Who can participate
Age range
14 Years – 50 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Pregnant women who test HIV-positive in antenatal care services at target health facilities
Exclusion Criteria:
* Pregnant women who arrived at health facilities who already have tested positive
* HIV-positive pregnant women who cannot start ART
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial focused on HIV-positive pregnant women in Mozambique starting antiretroviral therapy early — if I'm in a similar situation, how does the evidence from a completed study like this one apply to my specific care options here?
2The trial measured retention at 30 days and adherence at 90 days as its main outcomes — what did those results suggest about how well women were able to stay on treatment in those early months, and does that change how you'd approach my treatment plan?
3Since this study was done in Central Mozambique, how confident are you that its findings translate to my healthcare setting, given potential differences in access to care, support systems, and available medications?
4This trial is listed as Phase NA, meaning it was more of an observational or implementation study rather than a drug trial — does that mean its findings are more about how care is delivered than about whether a specific medication works, and how should I weigh that when making decisions about my own treatment?
5Are there current standard-of-care guidelines for starting ART during pregnancy that already incorporate findings from studies like this one, and would following those guidelines be a better first step for me than looking for an active trial?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.