Compassionate Use of Omegaven in Children

Inclusion Criteria: * Live in or temporarily relocate to Oklahoma * Age less than 18 years, both sexes, all races * Have a direct bilirubin level of ≥2 mg/dL for two consecutive weeks after at least 14 days of parenteral nutrition * Received parenteral lipids at a maximum dose of 1.7 g/kg/day (24 g/kg over the two weeks prior) * Are not currently enrolled in another lipid emulsion study Exclusion Criteria: * Known food allergy to fish * Known metabolic disorder of lipid metabolism * Active coagulopathies (active bleeding or requiring blood product treatment in the prior 48 hours) * Medical condition likely to result in death in the next 30 days