The purpose of this sudy is to investigate the effects of a regular aerobic exercise on aerobic capacity, fatigue, depression, quality of life, perception of symptoms and disease activity in women with pSS.
Who can participate
Age range
18 Years – 65 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* female gender and age ≤ 65 years-old
* pSS diagnosed according to the American European Consensus Criteria (VITALI et al, 2002)
* corporal mass index \< 40.
Exclusion Criteria:
* use of beta-blocker therapy;
* severe manifestations on pulmonary, renal, neurologic or musculoskeletal system (from the disease or not);
* limiting or hindering their ability to walking performance
* those who had performed regular physical activity in the 6 weeks before trial.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial focused on fatigue as the main thing it measured in people with primary Sjögren's syndrome — can you tell me what the results showed, and whether aerobic exercise actually helped with fatigue in participants?
2Since this study is completed and wasn't a drug trial but an exercise intervention, does the evidence from it change your recommendations for how active I should be with my Sjögren's syndrome?
3The trial ran for 16 weeks — is that long enough to see meaningful changes in fatigue, or do we need longer-term data before drawing conclusions about exercise as part of my care plan?
4Are there any risks specific to Sjögren's syndrome — like joint pain, dryness, or fatigue flares — that I should be aware of before starting a structured aerobic exercise program similar to what this trial used?
5Given that this trial has finished, are there other ongoing studies or updated treatment approaches for Sjögren's-related fatigue that might also be worth exploring alongside or instead of an exercise program?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.