CompletedNot Applicable

Optic Nerve Sheath Diameter (ONSD) With the Raised PCO2 and Internal Jugular Venous Occlusion

Canada100 participantsStarted 2015-01

Plain-language summary

Monitoring the ICP is the most important aspect of the management of these patients. Recently, transorbital ultrasonography has gained popularity as a noninvasive bedside exam that has been shown to be useful in the diagnosis of raised ICP by evaluating the change in the optic nerve sheath diameter (ONSD). Transorbital ultrasonographic measurement of ONSD appears to be a noninvasive, relatively inexpensive bedside examination for the diagnosis of raised ICP. The investigators aimed to determine the changes in ONSD with acute controlled changes in ICP in healthy volunteers. The controlled changes in ICP will be produced by manipulating the PCO2 with the use of Respiract and jugular venous compression with the use of custom made neck collar.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: Adult healthy volunteers who are above the age of 18 ASA 1 Body mass index (BMI) less than and equal to 35 Neurologically normal subjects with no symptoms other than occasional non-severe headache Exclusion Criteria: BMI above 35 Lack of informed consent Language barrier Medical students and/or anesthesia residents going through the department as part of their rotation Pregnancy Frequent migraine headache

What they're measuring

Changes in ONSD in mm With Changes in ICP in Healthy Volunteers.

Timeframe: 1 day

Trial details

NCT IDNCT02361658

SponsorLashmi Venkatraghavan

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2017-05

Results submitted2023-05-24

View on ClinicalTrials.gov More Elevated Intracranial Pressure (ICP) trials