TerminatedNot Applicable

Study of the Cutaneous Reinnervation After Burn

Stopped: Difficulty to recruit all the patients

France6 participantsStarted 2015-08

Plain-language summary

The aim of this study is to understand why the regeneration of the cutaneous sensory nerve fibers is poor in post-burn scar. The presence or the lack of several molecular factors known to regulate neuronal cell development will be evaluate and compared within biopsies from healthy skin and post-burn scar.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Major patients * At least one year back deep burn (2nd and 3rd degrees), and allowing the comparison between the post-burn scar dermatome and the healthy opposite dermatome * Patients always followed in the service of Plastic surgery of the hospital of Brest * Informed consent and paper of the patient after information of the objective of the study and the protocol * Analog Visual scales for pain and/or pruritus (EVA): greater than or equal to 3 * Simple Verbal scales for the pain and/or the pruritus ( EVS): pain / pruritus moderated to intense * Membership to the Social Security Exclusion Criteria: * Allergy to xylocaine * Non-Caucasian patients * Treatments having an effect on the pain and/or the pruritus * Sun or UV exposure several days preceding or following the biopsies

What they're measuring

Number of the differences of expression of genes coding for regulating proteins of the innervation

Timeframe: 6 months

Trial details

NCT IDNCT02356354

SponsorUniversity Hospital, Brest

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2016-08

View on ClinicalTrials.gov More Post-burn Innervation trials