Comparative Effects of Moxonidine on Bone Metabolism, Vascular and Cellular Aging in Hypertensive… (NCT02355821) | Clinical Trial Compass
CompletedNot Applicable
Comparative Effects of Moxonidine on Bone Metabolism, Vascular and Cellular Aging in Hypertensive Postmenopausal Women
Russia114 participantsStarted 2015-04
Plain-language summary
This study evaluates the effect of moxonidine versus bisoprolol on collagen type 1 C-telopeptide in postmenopausal female patients with arterial hypertension and osteopenia.
Who can participate
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Female with age 45 years and older.
. Postmenopausal (absence of menstrual periods for a minimum of 12 months) at the moment of Informed Consent sign.
. Arterial hypertension grade I / II per ESH/ESC 2013 guidelines (diastolic pressure ≥ 90 and \<110 mm Hg, systolic pressure ≥140 and \<180 mm Hg).
. Not achieving BP targets \<140/90 mmHg either during antihypertensive therapy or naive.
. Absence of moxonidine or bisoprolol treatment at least 6 months before the study
. Osteopenia of lumbar spine and/or proximal part of the femur (osteoporosis T-score from -1 to -2.5 standard deviations \[SD\]) by X-Ray densitometry.
. Signed Informed Consent for participation in the study
Exclusion criteria
. Hypersensitivity to moxonidine, bisoprolol or any other ingredient of the respective formulations
. Any Contraindications for moxonidine, bisoprolol
. Osteoporosis (Т-score below - 2.5 SD).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Collagen Type 1 C-telopeptide
Timeframe: baseline (Visit 1) and 12 months (Visit 4)
Trial details
NCT IDNCT02355821
SponsorNational Research Center for Preventive Medicine