CompletedNot Applicable

Comparative Evaluation of Two Different Radiosurgery

Italy250 participantsStarted 2014-12-15

Plain-language summary

Randomized double arm phase III study to evaluate feasibility and safety of Gamma Knife radiosurgery and Linac Based (Edge) radiosurgery in brain metastatic patients

Who can participate

Age range18 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age 18 - 85 years * 1 - 4 brain metastases * Karnofsky performance status (KPS) ≥70 * RPA 1 or 2 * Histopathologically confirmation of primary solid tumor * Estimated survival ≥ 3 months as GPA score * Written informed consent Exclusion Criteria: * Prior WBRT * Age \> 85 years * KPS \< 70 * RPA 3 * Diagnosis of small cell lung cancer (SCLC) or Lymphoproliferative disease * Use of Avastin for at least 2 months after radiosurgery * Pregnant women

What they're measuring

Incidence of symptomatic radionecrosis

Timeframe: two years

Trial details

NCT IDNCT02355613

SponsorIstituto Clinico Humanitas

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-06

View on ClinicalTrials.gov More Metastases to Brain trials