TerminatedNot Applicable

EndoFLIP Use in Upper GI Tract Stenosis

Stopped: Lack of patient population

United States5 participantsStarted 2014-12

Plain-language summary

The purpose of this study is to investigate the use of a functional luminal imaging probe to characterize benign esophageal luminal strictures before and after dilation and identify predictors of response to therapy. Patients will be evaluated during endoscopy using functional luminal imaging (EndoFLIP; Crospon Medical Devices, Galway, Ireland) to characterize the geometry of benign luminal esophageal narrowing before and after dilation.

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * \> or = to 18 years of age * Referred for evaluation and treatment of benign esophageal luminal narrowing * Clinical diagnosis of benign esophageal luminal narrowing with documentation and imaging * Adult patients with benign refractory esophageal strictures referred for placement of an esophageal stent are eligible for this study * Willing and able to give informed consent * No condition or comorbidity which would prevent the patient from undergoing a successful upper endoscopy Exclusion Criteria: * \< 18 years of age * Pregnancy * History of prior endoscopic dilation\* (\*unless referred for placement of stent) * Coagulopathy * Inability to traverse the stricture using standard techniques * Patients unable to provide consent

What they're measuring

Collection of Measurements of the Luminal Narrowing Using EndoFlip

Timeframe: 12 Months

Trial details

NCT IDNCT02354716

SponsorUniversity of Pennsylvania

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2019-01

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