Determination of Genetic Polymorphisms in Chronic Chagas Cardiomyopathy

Inclusion Criteria: * Chagas disease diagnosis confirmed by 2 different serologies * Diagnosis of Chagas disease in both forms: indeterminate and cardiac ones, with and without ventricular dysfunction Exclusion Criteria: * Significant aortic stenosis * Mitral stenosis with a valve area inferior than 1,5 cm2 * Superior or moderated aortic and/or mitral regurgitation * Chronic use of immunosuppressive agents * Dialysis treatment of terminal renal failure * Fever on the last 48 hours or evidence of systemic infection in activity * Current abusive use of alcohol or illicit drugs * Any other comorbidities that impact patient's survival within the next 2 years * Liver disease in activity * Continuous use of steroids as treatment for chronic obstructive pulmonary disease * Hematologic, neoplastic or bone diseases * Homeostasis disturbances * Inflammatory diseases or chronic infectious diseases