CompletedNot Applicable

Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal Dystonia

United States20 participantsStarted 2015-10-28

Plain-language summary

This study seeks to compare the use of ultrasound and electrophysiologic techniques to target muscles for the treatment of spasticity and focal dystonia of the limbs. The purpose of this study is to investigate the use of two ways of locating the muscle for botulinum toxin (BoNT) injection for the treatment of focal hand dystonia and upper limb spasticity. Electrophysiologic guidance, using electrical stimulation, and ultrasound are the standard ways of locating muscles during a treatment of BoNT injection.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 years or older * Confirmed diagnosis of focal upper extremity dystonia (FHD) or upper limb spasticity * Stable onabotulinumtoxinA dose regimen with a stable response as judged by the physician and patient for at least 2 treatment sessions. Exclusion Criteria: * Contraindications to botulinum toxin * Pregnancy or nursing * Cognitive impairment that prevents reliable outcome measures of self-report

What they're measuring

Change in Patient Global Impression of Change

Timeframe: 4 weeks and 16 weeks

Trial details

NCT IDNCT02334683

SponsorIcahn School of Medicine at Mount Sinai

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-03-03

Results submitted2021-10-28

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