UnknownPhase 4

Effectiveness of Sugammadex in LMS Surgery

80 participantsStarted 2015-02

Plain-language summary

This study is comparing of rocuronium-sugammadex and succinylcholine during LMS surgery that is characterized by short operation time, required intense paralysis and ambulatory setting, has not been investigated.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * American Society of Anesthesiologist\[ASA\] class 1-3 * scheduled Laser microlaryngeal surgery under general anesthesia * written informed consent Exclusion Criteria: * suspected difficult tracheal intubation * disorder affecting neuromuscular blockade * known or suspected significant renal dysfunction * known or suspected severe hepatic dysfunction * history of malignant hyperthermia * allergy of opioids, neuromuscular blocking drugs or other medications used during general anesthesia * contraindication to pyridostigmine and/or atropine * pregnancy * breast feeding * body mass index \> 27kg/m2

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Recovery of T1 to 90%

Timeframe: from the end of surgery(when the surgeon removes the suspension laryngoscope ) to time when the TOF ratio is 0.9, up to 30 minutes

Surgical Rating Score

Timeframe: during surgery

Addition of Neuromuscular Blocking Agents

Timeframe: during surgery

Recovery of T1 to 10%

Timeframe: from the end of surgery to time when the TOF ratio is 0.1, up to 30 minutes

Trial details

NCT IDNCT02329964

SponsorKorea University Anam Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2015-08

Results submitted2015-08-04

View on ClinicalTrials.gov More Muscle Relaxation trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Recovery of T1 to 90%

Timeframe: from the end of surgery(when the surgeon removes the suspension laryngoscope ) to time when the TOF ratio is 0.9, up to 30 minutes

Surgical Rating Score

Timeframe: during surgery

Addition of Neuromuscular Blocking Agents

Timeframe: during surgery

Recovery of T1 to 10%

Timeframe: from the end of surgery to time when the TOF ratio is 0.1, up to 30 minutes