UnknownNot Applicable

Effects of Limb Ischemic Postconditioning in Young sICAS

China100 participantsStarted 2015-03

Plain-language summary

The purpose of this study is to evaluate the protective effects of upper limb ischemic postconditioning on collateral circulationin young symptomatic intracranial atherosclerosis and the baseline characteristics of trial participants, as an open, randomized controlled, prospective controlled trial.

Who can participate

Age range18 Years – 45 Years

SexALL

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Inclusion criteria

✓. Age between 18 to 45 Years old;
✓. Symptomatic intracranial atherosclerotic stenosis (sICAS): cranial CTA/MRA/TCD/DSA confirm the diagnosis, patients got ischemic stroke or transient ischemic attack in the brain region supplied by the stenosis artery;
✓. National Institutes of Health Stroke Scale(NIHSS) score 0-15
✓. Written informed consent was signed.

Exclusion criteria

✕. Cerebral hemorrhage and other parts of the active bleeding disease;
✕. Severe aphasia, unable to express himself;
✕. A history of brain tumor, brain trauma, cerebral embolism or other brain lesions;
✕. Severe lesions of severe cardiac, liver or kidney disease, malignancy or other systemic organ dysfunction;
✕. Blood Pressure\< 90 mmHg/60 mmHg or \>200 mmHg/110 mmHg after treatment;
✕. Dementia and mental illness;
✕. Using angiotensin-converting enzyme inhibitors;
✕. A history of major surgery or trauma 4 weeks prior to admission;

What they're measuring

Mean Change of Collateral Circulation from Baseline and at 6 months

Timeframe: Baseline and at 6 months

Trial details

NCT IDNCT02323425

SponsorXi'an Jiaotong University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2018-03

Contact for this trial

Meng Wei, Master

+8613572516964 67183723@qq.com

View on ClinicalTrials.gov More Stroke trials