Neurophysiological Measures of Auditory Perception and Rehabilitation in Cochlear Implanted Patients (NCT02323256) | Clinical Trial Compass
CompletedNot Applicable
Neurophysiological Measures of Auditory Perception and Rehabilitation in Cochlear Implanted Patients
France91 participantsStarted 2014-07
Plain-language summary
This study aims at investigating new automatic fitting techniques for cochlear implant patients based on objective measures. For this reason, the evolution of these neurophysiological measures, expressing the encoding of pure tones and speech, will be characterized in cochlear implanted patients as a function of post-implantation time and will be compared to those of normal hearing subjects. Moreover, the effect of auditory training with new tools based on serious games will be assessed.
Who can participate
Age range1 Year – 70 Years
SexALL
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Inclusion Criteria:
* native French speaker
* no medical treatment for behavior or neurological disorders
* normal or corrected vision
* right-handed
* normal ORL examination
* valid affiliation to social security
* absence of participation to another study
For the cochlear implanted patients:
* aged from 1 to 70
* bilateral severe to profound deafness
* cochlear implant
* congenital deafness, pre or post lingual
For the normal-hearing subjects:
* Aged from 18 to 70
* Normal tonal audiometry
Exclusion Criteria:
* No signed consent
* Treatment for depression, epilepsy, Parkinson's or Alzheimer's disease
* Physical health deficiency
* Mental retardation
* Neurological or psychiatric disease incompatible with the testing procedure
* Schooling in a foreign language
* Foreign language spoken at home with both parents
* Invalid social security
* For the normal hearing subjects, no known hearing deficits
What they're measuring
1
Amplitude of auditory steady state responses ASSR
Timeframe: one year at least after CI activation
2
Spectro-temporal analysis of speech-ABR
Timeframe: one year at least after CI activation
3
Acoustic Change Complex ACC
Timeframe: one year at least after CI activation
4
amplitudes and latencies of P1/N1/P2 complex and Mismatch Negativity MMN
Timeframe: one year at least after CI activation
5
Evolution of amplitude of auditory steady state responses ASSR
Timeframe: 1 month, 3 months, 6 months, 9 months and 12 months after CI activation
6
Evolution of spectro-temporal analysis of speech-ABR
Timeframe: 1 month, 3 months, 6 months, 9 months and 12 months after CI activation
7
Acoustic Change Complex ACC
Timeframe: 1 month, 3 months, 6 months, 9 months and 12 months after CI activation
8
amplitudes and latencies of P1/N1/P2 complex and Mismatch Negativity MMN